ea0021p167 | Diabetes and metabolism | SFEBES2009
Schisano Bruno
, Radford Claire
, Harte Allison
, Mc Ternan Phillip
, Ceriello A
Background: Since it has been shown that markers of oxidative stress persist in endothelial cells that have been exposed for a prolonged time to chronic constant high glucose levels, long after glucose normalization, a phenomenon defined as metabolic memory, evaluation of chronic exposure to oscillating high glucose, its impact on the induction of cellular stress markers and the onset of a metabolic memory might be of pivotal interest. In doing so we al...